Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is particulate and the particles are of...
Patent
1991-10-08
1992-11-10
Housel, James C.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is particulate and the particles are of...
436 67, 436165, 436501, 436533, 436808, 436536, 435299, 435312, 422 58, 422 61, 422 72, 422102, G01N 3352, G01N 3372
Patent
active
051622378
ABSTRACT:
Analytical reaction cassette and method for performing sequential analytical assay procedures to determine the amount of an analyte in a liquid test mixture. The reaction cassette can be in the form of a substantially square container having a substantially horizontal axis of rotation and incorporated with one or more analytical reagents such that they are contacted with a liquid test mixture in a desired ordered sequence to perform a particular assay procedure. Corners provided by the substantially square configuration of the reaction cassette disrupt the flow of liquids disposed in the reaction cassette upon contact therewith to thereby agitate and mix such liquids. A liquid disposed in the reaction cassette is capable of being manipulated and mixed therein by rotating the reaction cassette about the horizontal axis at sufficiently low velocities wherein the transport of such liquid is noncentrifugal and due substantially only to gravitational force. The reaction cassette is particularly useful for performing immunoturbidimetric assays, e.g., for the determination of glycated hemoglobin.
REFERENCES:
patent: 4883763 (1989-11-01), Holen
patent: 4970171 (1990-11-01), Messenger et al.
patent: 4990075 (1991-02-01), Wogoman
Messenger Lowry J.
Nelson Christine D.
Wogoman Frank W.
Yip Kin-Fai
Housel James C.
Klawitter Andrew L.
Miles Inc.
Redding David
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