Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence
Reexamination Certificate
2007-08-21
2007-08-21
Helms, Larry R. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
8 to 10 amino acid residues in defined sequence
C530S300000
Reexamination Certificate
active
10471934
ABSTRACT:
Disclosed herein is a novel retinoblastoma binding protein-related gene that encodes an antigenic epitope, IKPSLGSKK (SEQ ID NO:3), which is differentially expressed in cancers, such as breast, lung, colon, pancreas, and ovarian cancer. Polynucleotides that encode and polypeptides that comprise the antigenic epitope and variants thereof are disclosed. Also, disclosed are methods of using the polynucleotides and polypeptides of the present invention in immunotherapies and immunoassays.
REFERENCES:
patent: 6399373 (2002-06-01), Bougueleret
patent: WO 0000607 (2000-01-01), None
patent: WO 0073801 (2000-12-01), None
Degruijl et al. Nature Medicine 5(10): 1124-1125, Oct. 1999.
Bodey et al. Anticancer Research 20: 2665-2676, 2000.
Mellman I. The Scientist 20(1): 47, 2006.
Benet et al. Pharmacological Basis of Therapeutics, 8th ed., pp. 3-13, and 16-32 enclosed.
Burgess et al. Journal of Cell Biology 111: 2129-2138, 1990.
Lazar et al. Molecular and Cellular Biology 8(3): 1247-1252, 1988.
Ibragimova et al. Biophysical Journal 77: 2191-2198, 1999.
Fu et al. EMBO Journal 15: 4392-4401, 1996.
Vallejo et al. Biochimie 82: 1129-1133, 2000.
Powell et al. Pharmacogenesis 8: 411-421, 1998, abstract only enclosed.
Jang et al. Clinical and Experimental Metastasis 15: 469-483, 1997, abstract only enclosed.
Duffy Brad
Helms Larry R.
Regents of the University of California
Smith , Gambrell & Russell, LLP
Sunby, Esq. Suzannah K.
LandOfFree
RBP1L1, a novel retinoblastoma binding protein-related gene... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with RBP1L1, a novel retinoblastoma binding protein-related gene..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and RBP1L1, a novel retinoblastoma binding protein-related gene... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3845020