Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
2011-06-21
2011-06-21
Jarrell, Noble (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
active
07964721
ABSTRACT:
A mercury selective fluorescent chemosensor for detecting mercury ions by a compound represented by formula 1 and a novel fluorescent sensitive compound prepared by introducing two aminopyrene functions as a fluorescent sensitive moiety into a binding site of the compound of formula 1 is used for selectively detecting mercury ions are provided. The mercury selective fluorescent sensitive chemosensor is a switch type chemosensor having ON-OFF-type Hg2+-selective fluorescence quenching behavior and is not affected by other coexistent metal ions. Changes in fluorescence of the compounds of formula 1 were analyzed by ratiometric approach using monomer and excimer emissions of the pyrene fluorophore to selectively signal the concentration of mercury ions. The chemosensor can detect mercury ions in a micromolar unit even in a solution including an excess of water. Accordingly, the mercury selective fluorescent chemosensor for detecting mercury ions can be used effectively in environmental and medical applications.
REFERENCES:
patent: 7615377 (2009-11-01), Lippard et al.
patent: 2005/0112769 (2005-05-01), Lippard et al.
Kim et al. Organic Letters, 2007, 9(6), 1129-32.
Kim et al. Tetrahedron Letters, 2006, 47, 497-500.
Caballero, et al., “Highly Selective Chromogenic and Redox or Fluorescent Sensors of Hg2+in Aqueous Environment Based on 1,4-Disubstituted Azines;”J. Am. Chem. Soc.(2005); vol. 127, 15666-15667.
Song, et al.; “Fluorogenic Hg2+—Selective Chemodosimeter Derived from 8-Hydroxyquinoline;”Organic Letters; (2006); vol. 8, No. 16, 3413-3416.
Takahashi, Y.; Kasai, H.; Nakanishi, H.; Suzuki, T. M. Angew;Chem., Int. Ed.2006, 45, 913.
Oehme, I.; Wolfbeis, O. S.;Mikrochim. Acta1997, 126, 177.
Bonfil, Y.; Brand, M.; Kirowa-Eisner;E. Anal. Chim. Acta2002, 464, 99.
Kollmannsberger, M.; Rurack, K.; Resch-Genger, U; Rettig, W; Daub JChem. Phys. Lett.2000, 329, 363.
Rurack, K; Sczepan, M.; Spieles, M.; Resch-Genger, U.; Rettig; W.Chem. Phys. Lett.2000, 320, 87.
Dujols, V.; Ford, F.; Czarnik, A. W.;J. Am. Chem. Soc.1997, 119, 7386.
Elizabeth M. Nolan, Stephen J. Lippard;.J. Materials. Chemistry.2005, 15, 2778.
Ahn Sangdoo
Chang Suk-Kyu
Choi Myung Gil
Kim Jun Soo
No Kyoung Tai
Chung-Ang University Industry-Academy Cooperation Foundation
Hochberg D. Peter
Jarrell Noble
Mellino Sean F.
Smola Daniel J.
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