Optics: measuring and testing – For light transmission or absorption – Of fluent material
Patent
1980-08-18
1982-01-05
Corbin, John K.
Optics: measuring and testing
For light transmission or absorption
Of fluent material
250565, 422 68, G01N 2101
Patent
active
043091121
ABSTRACT:
A method and apparatus for the detection of the magnitude of selected chemical substances in a biological fluid by fixed rate analysis. Photometric analysis is performed sequentially upon a standard solution and then upon an unknown sample to determine the rate reaction in each. The method and apparatus minimize or eliminate error in equipment drift and calibration. The rate reaction is manually initiated in a standard solution carrying a known amount of a chemical substance. The standard is then placed into a photodetector circuit to produce a voltage representing optical density which increases at a constant but unknown rate during the reaction. The time required for the voltage to change from a base-line level to a selected and pre-set value is then measured and stored as a calibration reference time. Then, the rate reaction in the sample carrying an unknown amount of the chemical substance is initiated and the standard is replaced by the sample in the same photodetector circuit to produce a voltage representing optical density of the unknown sample. The voltage representing the optical density of the unknown sample increases at a constant but unknown rate and the rate is proportional to the amount of chemical substance in the sample. The voltage level at the end of the calibration reference time represents the change in the optical density of the unknown sample which, in turn, indicates the amount of chemical substance in the sample with respect to the standard sample. The voltage level is then provided to a display which indicates the amount of the chemical substance in the sample.
REFERENCES:
patent: 3542515 (1970-11-01), Scott
patent: 3565535 (1971-02-01), Monell
patent: 3633012 (1972-01-01), Wilhelmson et al.
patent: 3634868 (1972-01-01), Pelavin et al.
patent: 3703336 (1972-11-01), Rosse et al.
patent: 3748044 (1973-07-01), Liston
patent: 3952206 (1976-04-01), Liedholz
patent: 3989382 (1976-11-01), Kent et al.
patent: 4035087 (1977-07-01), Mori et al.
patent: 4061469 (1977-12-01), DuBose
Ashley Holvor W.
Li Vincent H.
Arnold Bruce Y.
Corbin John K.
Sherwood Medical Industries Inc.
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