Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-04-04
2006-04-04
Hayes, Robert C. (Department: 1649)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07022818
ABSTRACT:
There is disclosed a novel mammalian receptor protein designated GFRα-4 and the nucleic acid sequence encoding therefor. Also provided is an expression vector comprising the nucleic acid sequence and host cells transformed or transfected with the vector. Host cells expressing the receptor may be used to identify agonists or antagonists in relation to the receptor.
REFERENCES:
patent: WO 97/33912 (1997-09-01), None
patent: WO 99/14235 (1999-03-01), None
patent: WO 99/50298 (1999-10-01), None
patent: WO 00/05375 (2000-02-01), None
Rudinger, In “Peptide Hormones”, (ed. J.A. Parsons) Universisty Park Press, Baltimore (1976).
Jane Thompson, Epaminondas Doxakis, Luzia G.P. Pinon, Philip Strachan, Anna Buj-Bello, Sean Wyatt, Vladimir L. Buchman, and Alun M. Davies, “GFRα-4, a New GDNF Family Receptor” , Mol. Cell. Neudrosci. 11, 117-126(1998).
Yasushi Enokido, Fred De Sauvage, Jo-Anne Hong, Natalia Ninkina, Arnon Rosenthal, Vladimir L. Buchman and Alun M. Davies, “GRFα-4 and the tyrosine kinase Ret form a functional receptor complex for persephin”, Current Biology 8, 1019-1022(1998).
Mart Saarma, Hannu Sariola, “Other Neurotrophic Factors: Gliat Cell Line-Derived Neurotrophic Factor (GDNF)”, Microscopy Research and Technique, 45:292-302(1999).
Teresa M. Gunn, Kimberly A. Miller, Lin He, Richard W. Hyman, Ronald W. Davis, Arezou Azarani, Stuart F. Schlossman, Jonathan S. Duke-Cohan, Gregory S. Barsh, “The mouse mahongany locus encodes a tansmembrance form of human attractin”, Nature vol. 398, 152-156,(1999).
Maria De Fatima Bonaldo, Gregory Lennon, and Marcelo Bento Soares, “Normalization and Substraction: Two Approaches to Facilitate Gene Discovery”, Genome Research, 6:791-806,(1996).
Maria Lindahl, Tonis Timmusk, Jari Rossi, Mart Saarma, Matti S.Airaksinen, “Expression and Alternative Splicing of Mouse Gfra4 Suggest Roles in Endocrine Cell Development”, Molecular and Cellular Neuroscience 15, 522-533(2000).
Stefan Masure, Miroslav Cik, Evert Hoefnagel, Christopher A. Nosrat, Ilse Van Der Linden, Rizaldy Scott, Paul Van Gompel, Anne S. J. Lesage, Peter Verhasselt, Carlos F. Ibanez, Robert D.Gordon, “Mammalian GFRα-4, a divergent member of the GFRα family of coresceptors for GDNF family ligands, is a receptors for the neurotrophic factor persephin”, American Society for Biochemistry and Molecular Biology, Inc., 1-36(2000).
Matti S. Airaksinen, Alexey Titievskky, Mart Saarma, GDNF Family Neurotrophic Factor Signaling: Four Masters, One Servant?, Molecular and Cellular Neuroscience 13, 313-325(1999).
Cik Miroslav
Hoefnagel Evert W.
Masure Stefan L. J.
Donnelly Laura
Hayes Robert C.
Janssen Pharmaceutica N.V.
LandOfFree
Rat neurotrophic factor receptor, GFRα-4 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rat neurotrophic factor receptor, GFRα-4, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rat neurotrophic factor receptor, GFRα-4 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3542697