Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1997-02-26
1999-09-07
Carlson, Karen Cochrane
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
4353201, 435325, 536 232, 536 2431, C12N 510, C12N 964, C12N 1557, C12N 1563
Patent
active
059486694
ABSTRACT:
Rat cathepsin k polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing rat cathepsin k polypeptides and polynucleotides in the design of protocols for the treatment of osteoporosis, periodonatal disease, arthritis, cancer, tumor metastasis, and Paget's disease, among others, and diagnostic assays for such conditions.
REFERENCES:
patent: 5501969 (1996-03-01), Hastings et al.
Shi et al., "Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2", FEBS Letters, 357, pp. 129-134 (1995).
Accession No. AF010306, Payne et al., "Rattus norvegicus cathepsin K mRNA" (1997).
Rantakokko et al., FEBS Letters 393:307-313, 1996.
Tezuka et al., J. Biol. Chem. 269:1106-1109, 1994.
Hadman et al., Oncogene 12:135-142, 1996.
Hill et al., J. Cell. Biochem. 56:118-130, 1994.
Gelb et al., Science 273:1236-1238, 1996.
Drake, et al., "Identification of a Novel Osteoclast-Selective Human Cystein Proteinase", J. Bone Miner. Res., 9:S177, 1994.
Brun Kimberly
Feild John A.
Carlson Karen Cochrane
Han William T.
King William T.
Kinzig Charles M.
SmithKline Beecham Corporation
LandOfFree
Rat cathepsin K polynucleotide and polypeptide sequence does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rat cathepsin K polynucleotide and polypeptide sequence, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rat cathepsin K polynucleotide and polypeptide sequence will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1803996