Rare earth cryptates, processes for their preparation, synthesis

Details Rare earth cryptates, processes for their preparation, synthesis Rare earth cryptates, processes for their preparation, synthesis

1994-06-09

1995-10-10

Tucker, Philip

Organic compounds -- part of the class 532-570 series

Organic compounds

Rare earth containing

534 16, 540465, 540467, 540469, C07F 500

Patent

active

054571855

ABSTRACT:
The invention relates to rare earth cryptates consisting of at least one rare earth salt complexed by a macropolycyclic compound corresponding to one of formulae I or II below, in which:
the ring ##STR1## is the N.sub.2 O.sub.4 macrocycle, the N.sub.2 O.sub.3 macrocycle or the bis-bipyridine macrocycle;
Y is a spacer arm or group which consists of a divalent organic radical selected from linear or branched C.sub.1 to C.sub.20 alkylene groups optionally containing one or more double bonds and/or optionally being interrupted by one or more heteroatoms such as oxygen, nitrogen, sulfur or phosphorus, or from C.sub.5 to C.sub.8 cycloalkylene groups or C.sub.6 to C.sub.14 arylene groups, the said alkylene or arylene groups optionally being substituted by alkyl, aryl or sulfonate groups;
Z is a functional group capable of bonding covalently with a biological substance;
R is a methyl group or represents the group --Y--Z; and

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