Rapidly soluble drug composition

Details Rapidly soluble drug composition Rapidly soluble drug composition

2006-11-28

2006-11-28

Gollamudi, Sharmilla S. (Department: 1616)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S464000, C424S489000, C514S951000, C514S960000, C514S249000

Reexamination Certificate

active

07141249

ABSTRACT:
A fast-dissolving pharmaceutical composition comprising micronized (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3′-pyrrolidine-1,2′,3,5′-tetrone (hereinafter, referred to as AS-3201). The present pharmaceutical composition has improved dissolution characteristics as well as a good bioavailability.

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“Design and Evaluation of Peroral Pharmaceutical Preparations (in Japanese)”, edited by Mitsuru Hashida, Yakygyo Jihosha, Feb. 10, 1995, pp. 81-84, 168-171, Trans. Sep. 20, 2000.
“Practical Drug Additives (in Japanese)”, Research Team Concerning Drug Additives, Mar. 5, 1974, pp. 258-259, Trans Sep. 26, 2000.

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