Rapidly soluble aspirin compositions and method

Details Rapidly soluble aspirin compositions and method Rapidly soluble aspirin compositions and method

1989-08-25

1992-10-20

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

514159, 424 43, 424 44, 424466, A61K 3160

Patent

active

051570300

ABSTRACT:
The reaction rate between aspirin and an equimolar amount of alkaline compound in an aqueous medium is increased by the inclusion of a surface-active agent such as lecithin or an oxyethylene-oxypropylene polymer. As a result the aspirin is completely dissolved within the aqueous medium to increase its availability in the body and reduce damage to gastro-intestinal mucosa, the primary adverse side effect of aspirin.

REFERENCES:
patent: 4687662 (1987-08-01), Schobel
patent: 4942039 (1990-07-01), Duvall et al.

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