Rapidly solubilized AHF composition and process for preparing sa

Details Rapidly solubilized AHF composition and process for preparing sa Rapidly solubilized AHF composition and process for preparing sa

1976-10-05

1978-05-16

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424176, 424361, A61K 3514, A61K 4700

Patent

active

040899446

ABSTRACT:
The rate of solubility of a freeze-dried solid composition containing therapeutic amounts of anti-hemophilic factor (AHF) is greatly increased by carrying out the solubilization in the presence of at least a critical threshold amount of a water soluble carbohydrate. The carbohydrate is incorporated into the AHF composition in sufficient quantity to provide at least 2 weight units of carbohydrate (expressed in grams) per 100 volume units of AHF solution (expressed in milliliters). This enhanced rate of solubility permits rapid treatment of hemophilic patients.

REFERENCES:
patent: 2826533 (1958-03-01), Fowell
patent: 3057781 (1962-10-01), Mace et al.
patent: 3973002 (1976-08-01), Hagan et al.

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