Rapidly resorbable glibenclamide

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A01N 916

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active

040606341

ABSTRACT:
A blood sugar lowering composition comprising as the active material particulate glibenclamide having a surface area of about 3 to 10 m.sup.2 /g in admixture with a pharmacologically acceptable non-ionic wetting agent present in about 2 to 20 times the weight of the glibenclamide. The preferred wetting agent is polyoxyethylene stearate present in about 5 to 10 times the weight of the glibenclamide.

REFERENCES:
patent: 3507954 (1970-04-01), Weber et al.
Remington's--Pharmaceutical Science--13th ed--J. Hoover Hack Publ. Co.--Easton, Pa., 1965, pp. 195-197, 332-333 & 420.

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