Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1994-02-03
1998-09-15
Webman, Edward J.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424466, 424474, 424482, 424486, 424488, 424499, 514960, A61K 920, A61K 928, A61K 914, A61K 946
Patent
active
058075763
ABSTRACT:
The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of the present invention comprises up to four steps. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.
REFERENCES:
patent: 4013784 (1977-03-01), Speiser
patent: 4572832 (1986-02-01), Kigasawa et al.
patent: 5082667 (1992-01-01), Van Scoik
patent: 5178878 (1993-01-01), Wehling et al.
patent: 5215756 (1993-06-01), Gole et al.
Allen, Jr. Loyd V.
Davies John Desmond
Wang Bingnan
Janssen Pharmaceutica Inc.
The Board of Regents of the University of Oklahoma
Webman Edward J.
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