Rapidly dissolving dosage form

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

Patent

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Details

424466, 424474, A61K 920, A61K 928, A61K 946

Patent

active

057764913

ABSTRACT:
The present invention concerns a particulate support matrix, a solid dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into the oral cavity.
First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.

REFERENCES:
patent: 4013784 (1977-03-01), Speiser
patent: 4572832 (1986-02-01), Kigasawa et al.
patent: 5082667 (1992-01-01), Van Scoik
patent: 5178878 (1993-01-01), Wehling et al.
patent: 5215756 (1993-06-01), Gole et al.

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