Rapidly disintegrating sustained release cefuroxime axetil...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

Reexamination Certificate

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Details

C424S462000, C424S468000, C424S474000, C424S482000, C514S772100, C514S772400

Reexamination Certificate

active

06932981

ABSTRACT:
A fast disintegrating controlled release oral composition comprising a core material containing cefuroxime axetil present as controlled release form, the cefuroxime axetil being provided with an outer coating of a copolymer selected from aqueous dispersions of enteric methacrylic acid and methacrylic acid esters anionic copolymers having carboxyl group as the functional group or mixtures thereof and an inner coating of a sustained-release copolymer selected from aqueous dispersions of acrylate and methacrylate pH independent copolymers having quaternary ammonium group as a functional group or mixtures thereof, and optionally probenecid. Additionally, the coating composition may contain plasticizers. The composition is suitable for once daily administration.

REFERENCES:
patent: 4325960 (1982-04-01), Godfredsen et al.
patent: 5580578 (1996-12-01), Oshlack et al.
patent: 6372255 (2002-04-01), Saslawski et al.
patent: 19835823 (1999-10-01), None
patent: 0280571 (1988-08-01), None
patent: 9324109 (1993-12-01), None
patent: WO 99/44614 (1999-09-01), None
patent: 0076479 (2000-12-01), None

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