Rapidly disintegrable tablet composition and method

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Gas produced in situ by chemical reaction

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424 22, 424 35, 426 86, 426590, 426591, 426594, A61K 926, A61K 936, A61K 962, A61K 904

Patent

active

044141980

ABSTRACT:
Rapidly water-disintegrable tablet is provided comprising an active ingredient such as a foodstuff or medicament, and distributed therewithin a small but effective amount of a tablet disintegrable system comprising an unreacted, intimate mixture of alginic acid and a water soluble metal carbonate in proportions reactive to form metal alginic acid salt and carbonic acid when the tablet is placed in water, the bulk of the salt acting to swell the tablet and the carbonic acid acting to simultaneously release carbon dioxide within the swelling tablet whereby rapid disintegration of the tablet is effected.

REFERENCES:
patent: 2889226 (1959-06-01), Hinkley
patent: 3903255 (1975-09-01), Gusman
patent: 4079125 (1978-03-01), Sipos
patent: 4172120 (1979-10-01), Todd
patent: 4344968 (1982-08-01), Aoda

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