Rapidly disintegrable pharmaceutical composition

Details Rapidly disintegrable pharmaceutical composition Rapidly disintegrable pharmaceutical composition

2007-03-13

2007-03-13

Tran, S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S451000, C424S455000, C424S464000, C424S466000, C424S469000, C424S470000

Reexamination Certificate

active

10998659

ABSTRACT:
The present invention relates to a pharmaceutical composition useful for rapid disintegration, which comprises a sparingly soluble medicament held on a gel-forming water-soluble polymer as a solid dispersion, wherein it contains a salt substance that comprises an alkali and a weak or strong acid and has an endothermic standard enthalpy of solution or heat of solution. Since rapid disintegration of the pharmaceutical composition of the present invention and rapid dissolution of the medicament contained in the preparation can be made in the digestive tracts pH-independently, good bioavailability can be attained.

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