Rapidly cleavable substrate for HIV protease

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence

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530329, 435 23, 514 15, 514 16, 548335, 436 86, C12Q 137, C07K 706, C07D20702

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active

050934775

ABSTRACT:
A rapidly cleavable substrate for HIV protease Hepta- to nona-peptides of the formula

REFERENCES:
patent: 4952493 (1990-08-01), Kettner et al.
patent: 5011910 (1991-04-01), Marshall et al.
D. Heinova et al., Chemical Abstract 113:293, Abstract #20146, 1990, Abstract of Czech. CS 261,172, Jun. 15, 1989.
Vasella et al., Helvetica Chimica Acta, vol. 66, No. 4, pp. 1241-1252 (1983).
Schneider et al., Cell. vol. 54, pp. 363-368 (Jul. 29, 1988).

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