Multicellular living organisms and unmodified parts thereof and – Method of using a transgenic nonhuman animal in an in vivo...
Reexamination Certificate
2007-08-06
2010-02-02
Bertoglio, Valarie (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Method of using a transgenic nonhuman animal in an in vivo...
C800S020000
Reexamination Certificate
active
07655832
ABSTRACT:
The present invention provides a method of simultaneously screening at least two candidate agents for an activity affecting regeneration of an embryonic teleost. According to this method, for each agent, a fin of the embryonic teleost is amputated. Next, the amputated teleost is incubated with the candidate agent for a specified period of time. After this period of time, the amputated teleost is imaged. This image is compared to an image of an amputated teleost that was incubated for the specified period of time in the absence of the candidate agent. When comparing the images, a change in morphology of the amputated fin of the embryonic teleost incubated in the presence of the candidate agent compared to the amputated fin of the embryonic teleost raised in the absence of the candidate agent indicates that the candidate agent affects regeneration.
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Mathew Lljoy K.
Tanguay Robert L.
Bertoglio Valarie
Klarquist & Sparkman, LLP
The State of Oregon Acting by and Through the State Board of Hig
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