Rapid thermal cycling device

Details Rapid thermal cycling device Rapid thermal cycling device

2004-05-07

2009-11-10

Ciric, Ljiljana (Lil) V (Department: 3744)

Heat exchange

With timer, programmer, time delay, or condition responsive...

Means to heat or cool for predetermined periods of time

C422S105000, C435S287200

Reexamination Certificate

active

07614444

ABSTRACT:
A lid for a well plate is provided. A pin penetrates the lid and projects downwardly into a well of the well plate. An electrical charge is applied to the pin and an electrical charge of opposite polarity is applied to an electrically conductive portion of a corresponding well, generating a small flow of electrical current and corresponding electrical fields within the well. Charged materials, such as DNA, selectably are attracted to the pin and segregated from the liquid sample.

REFERENCES:
patent: 1006767 (1911-10-01), Mauger
patent: 1456005 (1923-05-01), Harris
patent: 2379474 (1945-07-01), Bramson
patent: 3379118 (1968-04-01), Perez
patent: 3616264 (1971-10-01), Ray
patent: 4038055 (1977-07-01), Varano et al.
patent: 4116777 (1978-09-01), Takátsy et al.
patent: 4286456 (1981-09-01), Sisti et al.
patent: 4420679 (1983-12-01), Howe
patent: 4468423 (1984-08-01), Hall
patent: 4481405 (1984-11-01), Malick
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4701415 (1987-10-01), Dutton et al.
patent: 4865986 (1989-09-01), Coy et al.
patent: 4889818 (1989-12-01), Gelfand et al.
patent: 4902624 (1990-02-01), Columbus et al.
patent: 4965188 (1990-10-01), Mullis et al.
patent: 4981801 (1991-01-01), Suzuki et al.
patent: 5038852 (1991-08-01), Johnson et al.
patent: 5061630 (1991-10-01), Knopf et al.
patent: 5236666 (1993-08-01), Hulette et al.
patent: 5333675 (1994-08-01), Mullis et al.
patent: 5432086 (1995-07-01), Fränzl et al.
patent: 5455175 (1995-10-01), Wittwer et al.
patent: 5489532 (1996-02-01), Charm et al.
patent: 5525300 (1996-06-01), Danssaert et al.
patent: 5601141 (1997-02-01), Gordon et al.
patent: 5602756 (1997-02-01), Atwood et al.
patent: 5604130 (1997-02-01), Warner et al.
patent: 5681492 (1997-10-01), Van Praet
patent: 5716842 (1998-02-01), Baier et al.
patent: 5721136 (1998-02-01), Finney et al.
patent: 5819842 (1998-10-01), Potter et al.
patent: 5863507 (1999-01-01), James
patent: 5939312 (1999-08-01), Baier et al.
patent: 6153426 (2000-11-01), Heimberg
patent: 6171850 (2001-01-01), Nagle et al.
patent: 6197575 (2001-03-01), Griffith et al.
patent: 6312960 (2001-11-01), Balch et al.
patent: 6331441 (2001-12-01), Balch et al.
patent: 6338802 (2002-01-01), Bodner et al.
patent: 6372486 (2002-04-01), Fripp
patent: 6423536 (2002-07-01), Jovanovich et al.
patent: 6451261 (2002-09-01), Bodner et al.
patent: 6479301 (2002-11-01), Balch et al.
patent: 6489112 (2002-12-01), Hadd et al.
patent: 6627421 (2003-09-01), Unger et al.
patent: 6948843 (2005-09-01), Laugharn, Jr. et al.
Cao, T., “A Simple and Inexpensive System to Amplify DNA by PCR,”Biotechniques, 7(6):566-7, Jun. 1989.
Chapin, K., et al., “Evaluation of a Rapid Air Thermal Cycler for Detection ofMycobacterium tuberculosis,” J Clin Microbiol., 35(8):2157-9, Aug. 1997.
Civitello, A., et al., “A Simple Protocol for the Automation of DNA Cycle Sequencing Reactions and Polymerase Chain Reactions,”DNA Seq., 3(1):17-23, 1992.
Constans, A., “Some Like it Hot: A Thermal Cycler Roundup,”The Scientist, 15(24):32, Dec. 10, 2001.
Denton et al., PCR Protocols: A Guide to Methods and Applications, “A Low-Cost Air-Driven Cycling Oven,” pp. 435-441, 1990.
Mai, M., et al., “Shortened PCR Cycles in a Conventional Thermal Cycler,”Biotechniques, 25(2):208-10, Aug. 1998.
Merriam-Webster's Collegiate Dictionary, Tenth Edition, Merriam Webster Incorporated, 1996, p. 959.
Perry and Green,Perry's Chemical Engineer's Handbook, 7thed., “Heat Transfer by Radiation,” pp. 5-23 to 5-42, 1997.
Soper, S., et al., “Sanger DNA-sequencing Reactions Performed in a Solid-phase Nanoreactor Directly Coupled to Capillary Gel Electrophoresis,”Anal Chem., 70(19):4036-43, Oct. 1, 1998.
Tret'iakov, A., et al., “Fast DNA Amplification in Small Ultrathin-wall Microplates,”Bioorg Khim., 23(6):526-8, Jun. 1997.
Weis, J., et al., “Detection of Rare mRNAs via Quantitative RT-PCR,”Trends Genet., 8(8):263-4, Aug. 1992.
Wilding, P., et al., “PCR in a silicon microstructure,”Clin Chem., 40(9):1815-8, Sep. 1994.
Wittwer, C., et al., “Minimizing the Time Required for DNA Amplification by Efficient Heat Transfer to Small Samples,”Anal Biochem., 186(2):328-31, May 1, 1990.
Wittwer, C., et al., “Rapid Cycle DNA Amplification: Time and Temperature Optimization.,”Biotechniques, 10(1):76-83, Jan. 1991.

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