Rapid thermal cycling device

Details Rapid thermal cycling device Rapid thermal cycling device

2006-04-11

2006-04-11

Ciric, Ljiljana (Department: 3753)

Heat exchange

With alarm, indicator, signal, register, recorder, test or...

C422S128000, C422S091000, C422S068100, C435S285300, C435S173100

Reexamination Certificate

active

07025120

ABSTRACT:
A lid for a well plate is provided. Pins penetrate the lid and project downwardly into the wells of the well plate. Thermal energy is applied to the upper end of the pin to regulate the temperature of liquid samples in the well plate. Ultrasonic energy is applied to the upper end of the pin to sonicate the liquid sample. An electrical charge is applied to the upper end of the pin to attract charged materials, such as DNA, and to selectably segregate charged materials from the liquid sample.

REFERENCES:
patent: 1006787 (1911-10-01), Mauger
patent: 1456005 (1923-05-01), Harris
patent: 2379474 (1945-07-01), Bramson
patent: 3379118 (1968-04-01), Perez
patent: 3616264 (1971-10-01), Ray et al.
patent: 4038055 (1977-07-01), Varano et al.
patent: 4116777 (1978-09-01), Takátsky et al.
patent: 4286456 (1981-09-01), Sisti et al.
patent: 4420679 (1983-12-01), Howe
patent: 4468423 (1984-08-01), Hall
patent: 4481405 (1984-11-01), Malick
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis et al.
patent: 4701415 (1987-10-01), Dutton et al.
patent: 4865986 (1989-09-01), Coy et al.
patent: 4889818 (1989-12-01), Gelfand et al.
patent: 4902624 (1990-02-01), Columbus et al.
patent: 4965188 (1990-10-01), Mullis et al.
patent: 4981801 (1991-01-01), Suzuki et al.
patent: 5038852 (1991-08-01), Johnson et al.
patent: 5061630 (1991-10-01), Knopf et al.
patent: 5236666 (1993-08-01), Hulette et al.
patent: 5333675 (1994-08-01), Mullis et al.
patent: 5432086 (1995-07-01), Fränzl et al.
patent: 5455175 (1995-10-01), Wittwer et al.
patent: 5489532 (1996-02-01), Charm et al.
patent: 5525300 (1996-06-01), Danssaert et al.
patent: 5601141 (1997-02-01), Gordon et al.
patent: 5602756 (1997-02-01), Atwood et al.
patent: 5604130 (1997-02-01), Warner et al.
patent: 5681492 (1997-10-01), Van Praet
patent: 5716842 (1998-02-01), Baier et al.
patent: 5721136 (1998-02-01), Finney et al.
patent: 5819842 (1998-10-01), Potter et al.
patent: 5863507 (1999-01-01), James
patent: 5939312 (1999-08-01), Baier et al.
patent: 6153426 (2000-11-01), Heimberg
patent: 6171850 (2001-01-01), Nagle et al.
patent: 6372486 (2002-04-01), Fripp
patent: 6423536 (2002-07-01), Jovanovich et al.
patent: 6627421 (2003-09-01), Unger et al.
patent: 6948843 (2005-09-01), Laugharn et al.
Soper, Williams, Lassiter, Zhang and Ford. 1998 Sanger DNA-sequencing reactions performed in a solid-phase nanoreactor directly coupled to capillary gel electrophoresis. Anal. Chem. 70, 4036-4043.
Wilding, Shoffner and Kricka. 1994 PCR in a Silicon Microstructure. Clin. Chem. 40, 1815-1818.
Chapin and Lauderdale, 1997 Evaluation of a Rapid Thermal Cycler for Detection of Mycobacterium tuberculosis. J. Clin. Micro. 2157-2159.
Mai, Barnes, Vafiadis and Polychronakos, 1998 Shortened PCR Cycles In A Conventional Thermal Cycler. Biotechniques 25, 208-210.
Wittwer and Garling, 1991 Rapid Cycle DNA Amplification: Time and Temperature Optimization. Biotechniques 10, 76-83.
Wittwer, Fillmore and Garlind, 1990 Minimizing the Time Required for DNA Amplification by Efficient Heat Transfer to Small Samples. Anal. Biochem 186, 328-331.
Cao, 1989 A simple and Inexpensive System to Amplify DNA by PCR. Biotechniques 7:6, 566-567.
Perry, and Green, 1997 Heat Transfer by Radiation. Perry's Chemical Engineers' Handbook 7thEd., 5-23 to 5-42.
Weis, Tan, Martin and Wittwer, 1992 Detection of Rare mRNAs via Quantitative RT-PCR. Trends in Gen. 8:8, 263-264.
Tret'iakov, Pantina, Kaboev, 1997 Fast DNA ampliciation in small ultra-thin wall microplates. Bioorg. Khim 23, 526-528.
Civitello, Richards and Gibbs, 1992 A simple protocol for the automation of DNA cycle sequencing reactions and polymerase chain reactions. DNA Seq. 3, 17-23.
*Denton, et al. , 1990 A Low-Cost Air-Driven Cycling Oven. PCR Protocols: A Guide to Methods and Applications 435-441.

Affiliated with

Also associated with

Rating

Rapid thermal cycling device does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Rapid thermal cycling device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rapid thermal cycling device will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3542451