Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Reexamination Certificate
2006-03-28
2006-03-28
Swartz, Rodney P (Department: 1645)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
C424S009200, C424S130100, C424S139100, C424S150100, C424S164100, C424S184100, C424S248100, C435S004000, C435S007100, C436S501000, C436S543000, C436S546000
Reexamination Certificate
active
07018616
ABSTRACT:
The present invention provides an assay for detection of serum antibodies toM. paratuberculosis. A tracer, comprising a carbohydrate antigen isolated fromM. paratuberculosisthat is conjugated to a fluorophore, is added to a serum sample from an animal to form a mixture. The fluorescence polarization of the mixture is then measured. The presence of serum antibodies toM. paratuberculosisis indicated by a fluorescence polarization value of the mixture that is higher than the fluorescence polarization value of a control. The present invention further provides a tracer for use in a fluorescence polarization assay for antibodies specific forM. paratuberculosis. The tracer comprises a carbohydrate antigen isolated fromM. paratuberculosisand conjugated to a fluorophore, such that the tracer is able to bind to antibodies specific forM. paratuberculosisto produce a detectable change in fluorescence polarization.
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Stilwell Kathryn Irene
Surujballi Om P.
Diachemix LLC
Her Majesty the Queen in Right of Canada as represented by the C
McDonnell Boehnen & Hulbert & Berghoff LLP
Swartz Rodney P
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