Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-07-28
2009-06-23
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120, C435S091200
Reexamination Certificate
active
07550268
ABSTRACT:
Methods, systems and kits are provided for detecting and quantifying multiple immunogens in a sample via consecutive addition of quantifiable extenders to immunogen bound complexes of immunogen binding agent attached to a DNA containing an RNA polymerase promoter.
REFERENCES:
patent: 5334702 (1994-08-01), Greene et al.
patent: 5663144 (1997-09-01), Greene et al.
patent: 5665539 (1997-09-01), Sano et al.
patent: 5919764 (1999-07-01), Greene et al.
patent: 5922553 (1999-07-01), Eberwine et al.
patent: 6022523 (2000-02-01), DeGrado et al.
Felix, A.M., “Applications of BOP reagent in solid phase synthesis”,Int. J. Pep. Res. 1988 31:231-238.
Harrison et al. United States Biochemical Pharma Ltd. (Europe), Watford, United Kingdom, 1996.
Hendrickson et al., “High sensitivity multianalyte immunoassay using covalent DNA-labeled antibodies and polymerase chain reaction”,Nucleic Acids Research1995 23(3):522-529.
Hruby V., “Conformational Restrictions of Biologically Active Peptides via Amino Acid Side Chain Groups”,Life Sci. 1982 31:189-199.
Joerger et al., “Analyte Detection with DNA-Labeled Antibodies and Polymerase Chain Reaction”,Clin. Chem. 1995 41(9): 1371-1377.
Leone et al., “Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA”,Nucleic Acids Res. 1998 26(9):2150-2155.
Park et al., “Rationally designed anti-HER2
eu peptide mimetic disables P185HER2
eutyrosine kinases in vitro and in vivo”,Nature Biotechnology2000 18:194-198.
In Peptides, E. Giralt and D. Andreu eds, ESCOM, Leiden, The Netherlands 1991.
Peterson & Greene, “Bacterial Expression and Characterization of Recombinant Biologically Active Anti-Tyrosine Kinase Receptor Antibody Forms”,DNA and Cell Biology1998 17(12):1031-1040.
Ploux O., “Cyclization of peptides on a solid support”,Int. J. Pep. Prot. Res. 1987 29:162-169.
Prasad et al., “Contrasting Solution Conformations of Peptides Containing α,α-Dialkylated Residues with Linear and Cyclic Side Chains”,Biopolymers1995 35:11-20.
Qian et al., “Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: A mechanism of interrecptor kinase activation and transphosphorylation”Proc. Natl Acad. Sci. 1994 91:1500-1504.
Reichmann et al., “Expression of an Antibody Fv Fragment in Myeloma Cells”,J. Mol. Biol. 1988 203:825-828.
Romani et al., “Synthesis of the trypsin fragment 10-25/75-88 of mouse nerve growth”,Int. J. Pep. Prot. Res. 1987 29:107-117.
Ruzicka et al., “Immuno-PCR with a Commercially Available Avidin System”,Science1993 260:698-699.
Sanna et al., “Rapid induction of tumor necrosis factor α in the cerebrospinal fluid after intracerebroventricular injection of lipopolysaccharide revealed by a sensitive capture immuno-PCR assay”Proc. Natl. Acad. Sci. 1995 92:272-275.
Schiller et al., “Synthesis of side-chain to side-chain cyclized peptide analogs on solid supports”,Int. J. Pep. Prot. Res. 1985 25:171-177.
Sheppard et al., “Acid-labile resin linkage agents for use in solid phase peptide synthesis”,Int. J. Peptide Res. 1982 20:451-454.
Skerra and Pluckthun, “Assembly of a Functional Immunoglobulin F. Fragment inEscherichia coli”, Science1988 240:1038-1041.
Suzuki et al., “Double Determinant Immuno-Polymearse Chain Reaction: A Sensitive Method for Detecting Circulating Antigens in Human Sera”,Jpn. J. Cancer Res. 1995 86:885-889.
Tan et al., “Molecular Beacons:A Novel DNA Probe for Nucleic Acid and Protein Studies”,Chemistry Eur. J. 2000 6(7) 1107-1111.
Zhou et al., “Universal immuno-PCR for ultra-sensitive target protein detection”,Nucleic Acid Res. 1993 21:6038-6039.
Horlick Kenneth R.
Licata & Tyrrell P.C.
Trustees of the University of Pennsylvania
Tung Joyce
LandOfFree
Rapid, sensitive and quantitative methods for tissue and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rapid, sensitive and quantitative methods for tissue and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rapid, sensitive and quantitative methods for tissue and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4136371