Rapid-releasing oral particle pharmaceutical preparation with un

Details Rapid-releasing oral particle pharmaceutical preparation with un Rapid-releasing oral particle pharmaceutical preparation with un

1990-07-18

1992-01-21

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424461, 424462, 424470, 424480, 424482, 424494, 424497, A61K 914

Patent

active

050826697

ABSTRACT:
A rapid-releasing oral particle pharmaceutical preparation with its unpleasant taste masked comprising a core and a film layer coating the core, the core at least containing a drug having an unpleasant taste and a water-swelling agent, and the film layer at least containing ethylcellulose and a water-soluble substance, the amount of the drug in the core being at most 40% (based on the final particle preparation and so on), the amount of the water-swelling agent being about 35% to about 70%, the amount of ethylcellulose in the film layer being about 3 to about 11%, and the amount of the water-soluble substance being about 0.1 to about 0.8 times the weight of the ethylcellulose.

REFERENCES:
patent: 4462982 (1984-07-01), Samejima et al.
patent: 4871549 (1989-10-01), Ueda et al.

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