Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1989-03-03
1991-04-23
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 424427, 424428, A61K 900
Patent
active
050098926
ABSTRACT:
Quick miosis with 24 hour control of intraocular pressure of patients undergoing extracapsular cataract extraction surgery is achieved by applying to the eyes of the patient during surgery acetylcholine as a first miotic agent and carbachol as a second miotic agent. Acetylcholine provides quick miosis while carbachol enhances the miotic effect while providing post-surgery control of intraocular pressure. The two miotic agents can be dissolved in a common saline carrier. The two agents can be combined in a unit dosage package by disposing acetylcholine in powder form in a first compartment and a solution of carbachol in a second compartment. The combined miotic agent of the invention is especially useful when substances which raise IOP such as viscoelastic agents are used during ocular surgery and/or with sensitive patients who enter the surgery with elevated pressure such as those suffering from glaucoma.
REFERENCES:
patent: 3870791 (1975-03-01), Haddad et al.
patent: 4405627 (1983-09-01), Masi et al.
patent: 4459309 (1984-07-01), Chiou
patent: 4490379 (1984-12-01), Podos et al.
patent: 4853224 (1989-08-01), Wong
Jacobs Marvin E.
Page Thurman K.
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