Chemistry: analytical and immunological testing – Pregnancy or ovulation
Reexamination Certificate
2005-10-13
2010-02-23
Wallenhorst, Maureen M (Department: 1797)
Chemistry: analytical and immunological testing
Pregnancy or ovulation
C436S063000, C436S086000, C436S087000, C436S164000, C436S172000, C435S007100, C435S007940
Reexamination Certificate
active
07666683
ABSTRACT:
The present invention relates to a novel method of determining the existence of a normal pregnancy which has a high likelihood of culminating in a term pregnancy, by measuring hyperglycosylated hCG in a pregnant woman and comparing the concentration of measured hyperglycosylated hCG with a predetermined value. A measurement of hyperglycosylated hCG above the predetermined value, for example, about 13 ng/ml, is evidence of a high likelihood of a normal pregnancy. A measurement below the predetermined value is evidence of an abnormal pregnancy (ectopic pregnancy or miscarriage). Further analysis of the patient in the event that the measurement falls below the predetermined value is made by intravaginal or abdominal ultrasound to determine whether or not the pregnancy is ectopic or will likely result in a spontaneous abortion (miscarriage). This point-of-care (POC), over-the-counter (OTC) or professional laboratory application is unexpectedly rapid and highly predictive of pregnancy outcome in women exhibiting symptoms of pregnancy.
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Coleman Henry D.
Sapone William J.
STC.UNM
Sudol R. Neil
Wallenhorst Maureen M
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