Rapid in vitro test for helicobacter pylori using saliva

Details Rapid in vitro test for helicobacter pylori using saliva Rapid in vitro test for helicobacter pylori using saliva

1992-04-30

1995-05-30

Bidwell, Carol E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 79, 435 792, 435 794, 435 795, 436518, 436527, 436530, 436531, G01N 33569

Patent

active

054200148

ABSTRACT:
The present invention contemplates a method for detecting contempory infection by H. pylori in a mammal comprising contacting a mucous secretion from said mammal with an antigen component from H. pylori for a time and under conditions sufficient for an IgG antibody in said mucous secretion specific to said antigen component to form a complex therewith and then subjecting said complex to a detecting means. Preferably, the antigen component is immobilized onto a solid support.

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B. Jones, "Fast molecule separation options", Laboratory Practice, 38(2), 64,67-68 (1989).
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Schaber et al. Journal of Clinical Microbiology, 27(2):327-330 (Feb. 1989).
Gronblad et al. Biological Abstracts, 83(6): Abstract No. 54423 (Mar. 15, 1987).
Witt, C. S. (Aug., 1990) "The Mucosal Immune Response to Helicobacter pylori" in Cripps, A. W., ed. Proceedings of a Satellite Meeting at the World Congress of Gastroenterology, Sydney, NSW, Australia; Mucosal Immunology Abstract, pp. 149-153.
Witt, et al. (Jun. 1990) "False Positive with Campylobacter pylori Antibody ELISA?" in McDonald, T. T., ed., Advances in Mucosal Immunology, Proceedings of the Fifth International Congress of Mucosal Immunology, Abstract 250, pp. 793-794.
Czinn, et al., (May 13-19, 1989, 90th Annual Meeting of the American Gastroenterological Association), Gastroenterology, vol. 96, No. 5, Part 2 (May 1989).

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