Rapid differentiation of bacteria using polyether antibiotics

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

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435 29, 435 31, 435 38, 435 39, 435805, 435810, C12Q 104

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048852392

ABSTRACT:
Rapid differentiation between viable gram-positive and gram-negative bacteria is accomplished with polyether antibiotics which are used in combination with a compound which is normally reducible by the bacteria. The antibiotics selectively and substantially inhibit the reduction of the reducible compound by gram-positive bacteria but do not substantially affect the reducing capacity of the gram-negative bacteria.

REFERENCES:
patent: 3923823 (1975-12-01), Gale et al.
patent: 4525453 (1985-06-01), Guardino et al.
patent: 4746607 (1988-05-01), Mura et al.
Finegold et al., "Bailey and Scott's Diagnostic Microbiology" 5th Ed. C. V. Mosby Co., St. Louis, 1978, p. 21.
Westley "Polyether Antibiotics" Marcel Dekker Inc., New York, 1982, pp. 1-51.

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