Rapid assay processor

Details Rapid assay processor Rapid assay processor

1986-05-02

1988-10-04

Marcus, Michael S.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436527, 436807, 436818, 436180, 435 5, G01N 33543

Patent

active

047756357

ABSTRACT:
A system and method is disclosed for the rapid detection and (or) purification of analytes in a sample. The system makes use of a fluid receptacle containing a capture reagent and a manifold having two ports. A sample containing an analyte disposed within the fluid receptacle is subjected to a capture reagent and processed by inserting the open end of the receptacle in one port. Vacuum, gas, reagents, and wash fluids are then applied to the second port to effect rapid interaction between the capture reagent and analyte, efficient washing of the capture reagent and detection and/or collection of the analyte.
The system and method provide a rapid safe, uncomplicated means of automating processes based on affinity complexation principles. Encompassed within this category of processes are immunoassays, nucleic acid hybridization tests and affinity separations.

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British Medical Bulletin, 30, 38-43, 1974.
Annals of Clinical Biochemistry, 18, 324-329, 1981, Michael Cais, Moshe Shimoni.

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