Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-04-25
1996-10-29
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 6, 435 912, 536 237, 536 2432, 536 2433, 935 8, 935 11, 935 17, 935 78, C12Q 170, C12Q 168, C12P 1934, C07H 2104
Patent
active
055695833
ABSTRACT:
The present invention relates to novel compositions comprising herpesvirus-specific oligonucleotides which are useful as primers to amplify particular regions of the genome either herpes simplex virus or cytomegalovirus during enzymatic nucleic acid amplification. The invention also provides a rapid, sensitive and specific method for the detection of the respective herpesvirus which may be present in a clinical specimen, using the herpesvirus-specific primers and enzymatic nucleic acid amplification; hybridization of amplified target sequences, if present, with one or more herpesvirus-specific oligonucleotide probes which are labeled with a detectable moiety; and detection of the detectable moiety of labeled oligonucleotide probe hybridized to amplified target sequences of herpesvirus DNA.
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Evans Mary J.
Greenberg Steven J.
Health Research , Inc.
Jones W. Gary
Myers Carla
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