Rapid and sensitive detection of antibiotic-resistant mycobacter

Details Rapid and sensitive detection of antibiotic-resistant mycobacter Rapid and sensitive detection of antibiotic-resistant mycobacter

1995-06-07

1998-01-27

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 2432, 536 2433, 935 77, 935 78, C12Q 168, C07H 2104, C07H 2102

Patent

active

057120951

ABSTRACT:
The invention relates to methods and oligonucleotide probe compositions useful for determining antibiotic resistance in Mycobacteria. Included are methods for freeing intact precursor ribosomal RNA from mycobacterial cells and for assaying the levels of pre-rRNA in the cells. Also claimed are methods useful in discovering new anti-mycobacterial therapeutic agents.

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