Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-05-29
1992-06-09
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514321, 540456, C07D49106, A61K 31395
Patent
active
051207273
ABSTRACT:
A rapamycin dimer of general formula (1) ##STR1## wherein A is --(CH.sub.2).sub.n --, --(CH.sub.2)n--(CH.dbd.CH)--(CH.sub.2).sub.m --, --(CH.sub.2)n--(--C.tbd.C--)--(CH.sub.2).sub.m --, ##STR2## substituted alkyl, substituted alkenyl, substituted alkynyl, and substituted aromatic; n=1-10, m=1-10 and n=m or n .noteq.m
or a pharmaceutically acceptable salt thereof, which is by virtue of its immunosuppressive activity is useful in treating transplantation rejection host vs. graft disease, autoimmune diseases, and diseases of inflammation.
REFERENCES:
patent: 3929992 (1975-12-01), Sehgal et al.
Can. J. Physiol. Pharmacol. 55,48 (1977).
Kao Wenling
Musser John H.
Vogel Robert L.
American Home Products Corporation
Bond Robert T.
Patton Walter
LandOfFree
Rapamycin dimers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rapamycin dimers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rapamycin dimers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1804650