Rapamycin 31-ester with N,N-dimethylglycine derivatives useful a

Details Rapamycin 31-ester with N,N-dimethylglycine derivatives useful a Rapamycin 31-ester with N,N-dimethylglycine derivatives useful a

1994-04-22

1995-05-16

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

540456, A61K 31395, C07D49116

Patent

active

054160863

ABSTRACT:
A derivative of rapamycin of general formula (1) and (2) ##STR1## wherein ##STR2## R.sup.2 =hydrogen, or lower alkyl having 1 to 6 carbon atoms; ##STR3## wherein X=hydrogen, lower alkyl having 1 to 6 carbon atoms, --CF.sub.3, --NO.sub.2, --OR.sup.2, NR.sup.2, SR.sup.2, or halogen;

REFERENCES:
patent: 5262423 (1993-11-01), Kao

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