Random array of microspheres

Details Random array of microspheres Random array of microspheres

2006-09-19

2006-09-19

Meeks, Timothy (Department: 1762)

Coating processes

Nonuniform coating

Applying superposed diverse coatings or coating a coated base

C427S002130, C427S202000, C427S337000, C427S338000, C427S372200, C427S407100, C427S407200, C427S412100, C427S412200

Reexamination Certificate

active

07108891

ABSTRACT:
A method of making a microarray comprising the steps of:providing a support;coating on the support a receiving layer to receive microspheres, the receiving layer being capable of undergoing sol/gel transition;coating on the receiving layer a dispersion of microspheres in a carrier fluid, wherein the carrier fluid contains at least one crosslinking agent and is capable of solvating the receiving layer;allowing the microspheres to partially submerge into the receiving layer;creating conditions to induce sol/gel transition in the receiving layer, thus immobilizing the microspheres;evaporating off the carrier fluid; andallowing crosslinking reaction between the receiving layer and the crosslinker in the carrier fluid.

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