Raman spectroscopic method for determining the ratio of...

Details Raman spectroscopic method for determining the ratio of... Raman spectroscopic method for determining the ratio of...

2009-01-08

2010-12-21

Gakh, Yelena G (Department: 1797)

Chemistry: analytical and immunological testing

Optical result

C436S171000, C546S273700

Reexamination Certificate

active

07855082

ABSTRACT:
The present invention relates to a novel method to determine the ratio of 5-methoxy and 6-methoxy isomers of omeprazole present in a mixture thereof. The method uses different Raman scattering efficiency values for the 5-methoxy and 6-methoxy isomers. This is of importance since the two isomers have different stability in the solid state in bulk form and in admixture with pharmaceutical excipients.

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