Raman signal-enhancing structures for Raman spectroscopy and...

Optics: measuring and testing – By dispersed light spectroscopy – With raman type light scattering

Reexamination Certificate

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Reexamination Certificate

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07639354

ABSTRACT:
Raman systems include a radiation source, a radiation detector configured to detect Raman scattered radiation, and a Raman signal-enhancing structure. The Raman signal-enhancing structure includes a first layer of Raman signal-enhancing material, a substantially monomolecular layer of molecules disposed on at least a portion of the first layer of Raman signal-enhancing material, and a second layer of Raman signal-enhancing material disposed on at least a portion of the substantially monomolecular layer of molecules. The second layer of Raman signal-enhancing material is disposed on a side of the layer of molecules opposite the first layer of Raman signal-enhancing material. Methods of performing Raman spectroscopy include providing such a Raman signal-enhancing structure, providing an analyte on the Raman signal-enhancing structure, irradiating the analyte and the structure, and detecting Raman scattered radiation.

REFERENCES:
patent: 7359048 (2008-04-01), Wang et al.
patent: 2002/0142480 (2002-10-01), Natan
patent: 2006/0056463 (2006-03-01), Wang et al.
patent: 2007/0252982 (2007-11-01), Wang et al.

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