Raman label and its conjugate in a ligand-binding assay for a te

Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens

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435968, 436164, 436172, 436501, 436518, 436524, 436525, 436537, 436543, 436546, 436547, 436548, 436800, G01N 33532, G01N 33533

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active

054459729

ABSTRACT:
A Raman label which, upon radiation, produces a detectable Raman scattering signal in a ligand-binding assay for an analyte in a test sample. A conjugate containing a Raman label attached to a specific binding member.

REFERENCES:
Rohr et al., "Immunoassay Employing Surface Enhanced Raman Spectroscopye", Analytical Biochemistry, 182, 1989, pp. 388-398.
Ni et al., "Surface Enhanced Resonance Raman Study of Axidin-Dye Interactions", Journal of Raman Spectroscopy, vol. 19, 1988, pp. 429-438.
Tran, "In situ identification of paper chromatogram spot by surface enhanced Raman scattering", Journal of Chromatography, 292 (2), 1984, pp. 432-438.
Thomas et al., "Resonance Raman Spectroscopic Studies of 2-(4'-hydroxyphenylazo) benzoic acid . . . ", Spectrochimica. Acta, 35A, 1979, pp. 1251-1255.
Pemberton et al., "Surface Enhanced Fluorescence of Basic Fuchsin of Roughened Silver Electrodes", SPIE vol. 1054 Fluorescnece Detection III (1989), pp. 113-121.

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