Ralstonia ahl-acylase gene

Details Ralstonia ahl-acylase gene Ralstonia ahl-acylase gene

2006-08-29

2006-08-29

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

Reexamination Certificate

active

07098014

ABSTRACT:
This invention provides a gene, qsbA, which encodes a protein useful for inactivating certain bacterial quorum-sensing signal molecules (N-acyl homoserine lactones) which participate in bacterial virulence and biofilm differentiation pathways. This gene was isolated fromRalstoniasp., strain XJ12B. The invention also provides the QsbA protein, which possesses N-acyl homoserine lactone inactivating activity.

REFERENCES:
patent: WO 01/98214 (2001-12-01), None
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Swiss-Prot. Accession Q9RYQ4, White et al., (two pages) (1999).
Embl Accession AE001836, White et al., (ninety pages) (1999).

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