RAIDD, a novel death adaptor molecule

Details RAIDD, a novel death adaptor molecule RAIDD, a novel death adaptor molecule

1997-12-19

2000-10-10

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

4353201, 4352523, 536 232, C12N 950, C12N 1500, C12N 120, C07H 2104

Patent

active

061300799

ABSTRACT:
The present invention relates to a novel molecule involved in the process of apoptosis. In particular, isolated nucleic acid molecules are provided encoding the human RAIDD protein and splice variants thereof--referred to as RAIDD-SV1 and RAIDD-SV2. RAIDD polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of RAIDD activity.

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