Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...
Reexamination Certificate
2011-07-19
2011-07-19
Kolker, Daniel E (Department: 1649)
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
C530S387300, C530S402000, C514S001100
Reexamination Certificate
active
07981424
ABSTRACT:
Disclosed are RAGE fusion proteins comprising RAGE polypeptide sequences linked to a second, non-RAGE polypeptide. The RAGE fusion protein may utilize a RAGE polypeptide domain comprising a RAGE ligand binding site and an interdomain linker directly linked to the N-terminus of an immunoglobulin CH2 domain. Also disclosed are RAGE fusion protein formulations and the use of the RAGE fusion proteins and RAGE fusion protein formulations as therapeutics for RAGE-mediated pathologies.
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Benjamin Eric J.
Mjalli Adnan M. M.
Rothlein Robert
Tian Ye Edward
Webster Jeffrey C.
Emch Gregory S
Kilpatrick Townsend & Stockton LLP
Kolker Daniel E
Transtech Pharma, Inc.
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