Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-03-25
2010-12-07
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S403000, C548S356100, C548S360100, C548S361100
Reexamination Certificate
active
07846959
ABSTRACT:
The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Raf. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention.
REFERENCES:
patent: 2004/103974 (2004-05-01), None
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Anand Neel Kumar
Blazey Charles M.
Bowles Owen Joseph
Bussenius Joerg
Costanzo Simona
Exelixis Inc.
McDonnell Boehnen & Hulbert & Berghoff LLP
Ward Paul V.
Wilson James O.
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