Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Reexamination Certificate
2001-07-25
2008-11-04
Hartley, Michael G. (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Reexamination Certificate
active
07445765
ABSTRACT:
A radiopharmaceutical for diagnostic imaging containing as an active ingredient a technetium-99m nitride heterocomplex comprising technetium-99m nitride and two different ligands coordinated therewith, i.e., a bisphosphinoamine compound as a π electron acceptor and a bidentate ligand as a π electron donor and represented by the following formula (I): [99mTc(N)(PNP)(XY)]+(I)wherein99mTc(N) is technetium-99m nitride, PNP is a bisphosphinoamine compound and XY is a bidentate ligand, is markedly accumulated in heart and adrenal glands and hence is useful for radiodiagnostic imaging of heart and adrenal glands.
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Bolzati Cristina
Boschi Alessandra
Duatti Adriano
Refosco Fiorenzo
Tisato Francesco
Hartley Michael G.
Nihon Medi+Physics Co., Ltd.
Perreira Melissa
Sughrue & Mion, PLLC
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