Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1992-11-06
1993-10-05
Lacey, David L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424 11, 534 10, 534 14, A61K 4300
Patent
active
052506665
ABSTRACT:
Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies. The radiolabeled antibodies, or catabolites thereof, demonstrate improved biodistribution properties, including reduced localization within the intestines.
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Fritzberg Alan R.
Gustavson Linda M.
Kasina Sudhakar
Srinivasan Ananthachari
Eisenschenk F. C.
Lacey David L.
NeoRx Corporation
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