Radionuclide labeling of vitamin B.sub.12 and coenzymes thereof

Details Radionuclide labeling of vitamin B.sub.12 and coenzymes thereof Radionuclide labeling of vitamin B.sub.12 and coenzymes thereof

1998-04-13

1999-12-21

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

536 2644, 424 111, 424 165, 424 91, A61K 5100, A61M 3614

Patent

active

060045337

ABSTRACT:
A compound useful for in vivo imaging of organs and tumors is provided of formula: ##STR1## wherein ##STR2## is a cobalamin, ##STR3## is derived from a corrin carboxylic acid group of said cobalamin, Y is a linking group and X is a chelating group, optionally comprising a detectable radionuclide or a paramagnetic metal ion, and n is 1-3.

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