Radiolabelled phenylethyl imidazole carboxylic acid ester...

Details Radiolabelled phenylethyl imidazole carboxylic acid ester... Radiolabelled phenylethyl imidazole carboxylic acid ester...

2008-04-15

2008-04-15

Shameem, Golam M. M. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S300100, C548S333500, C514S396000, C514S399000, C514S400000

Reexamination Certificate

active

07358369

ABSTRACT:
Halogenated carboxylic ester derivatives of phenylethyl imidazole, and their method of preparation are disclosed. Radio-halogenated forms of these compounds are ideally suited for positron-imaging of the adrenal glands, as it is known that these compounds demonstrate a selective and high rate of accumulation in the adrenals. The method of preparing these derivatives proceeds by the conversion of a stable, non-radioactive intermediate having trialkylstannyl leaving groups. These intermediates are efficiently converted to the corresponding halogenated forms by substitution of the trialkylstannyl group with the halogen or radiohalogen.

REFERENCES:
patent: 4770689 (1988-09-01), Van Gestel et al.
patent: 4851424 (1989-07-01), Allgeier
patent: 7189859 (2007-03-01), Zolle et al.

Affiliated with

Also associated with

Rating

Radiolabelled phenylethyl imidazole carboxylic acid ester... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Radiolabelled phenylethyl imidazole carboxylic acid ester..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Radiolabelled phenylethyl imidazole carboxylic acid ester... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2777880