Radiolabelled peptide compounds

Details Radiolabelled peptide compounds Radiolabelled peptide compounds

1992-02-05

1994-12-06

Stoll, Robert L.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530326, 930 22, 930 24, 930250, 534 10, 534 14, C07K 710, A61K 4300, A61K 4902

Patent

active

053711840

ABSTRACT:
A diagnostic composition suitable for administration to a warm-blooded animal comprising hirudin or a molecule capable of interacting with the hirudin receptor labeled with a radionuclide by means of a chelate ligand capable of administration to an animal to produce reliable visual imaging of thrombus.

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patent: 4746505 (1988-05-01), Jones et al.
patent: 4837003 (1989-06-01), Nicolotti
patent: 4965392 (1990-10-01), Fritzberg et al.
patent: 5037630 (1991-08-01), Fritzberg et al.
patent: 5080883 (1992-01-01), Lyle et al.
patent: 5175257 (1992-12-01), Kasina et al.
patent: 5187264 (1993-02-01), Verbruggen
Bryson et al., Inorg. Chem. 1990, vol 29, "Protecting Groups in the Preparation of Thiolate Complexes of Techetium", pp. 2948-2951.
Misra et al., Tetrahedron Letters, vol. 30, No. 15 (1989) "Synthesis of a Novel Diamino dithiol Ligand . . . ".

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