Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1993-01-13
1994-08-09
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
546 44, 435 29, 436 63, 424 145, A61K 4902, C07D48908
Patent
active
053364830
ABSTRACT:
The present invention is directed to radiolabeled N-substituted-6-iodo-3,14-dihydroxy-4,5.alpha.-epoxymorphinans, intermediates for producing the same, and a process for the preparation and methods of detecting opioid receptors. The radioimaging agent of the present invention has the following formula: ##STR1## wherein I is selected from the group consisting of .sup.123 L and .sup.125 ; and where R is alkyl, cycloalkylloweralkyl or allyl.
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Berman Karen F.
de Costa Brian R.
Iadarola Michael J.
Rice Kenner C.
Rothman Richard B.
Covert John M.
Lovering Richard D.
The United States of America as represented by the Department of
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