Radiolabeled derivatives of folic acid

Details Radiolabeled derivatives of folic acid Radiolabeled derivatives of folic acid

1976-09-29

1981-06-30

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 2601125R, 544258, A61K 4300, C07D47504, G01T 116

Patent

active

042762804

ABSTRACT:
Derivatives of folic acid wherein the .alpha.-carboxyl group of the glutamyl moiety is substituted with a radical which is capable of being radioiodinated, such as, substituted and unsubstituted tyrosyl and histidyl. The radioiodinated derivatives can be employed as tracers for the assay of folates.

REFERENCES:
patent: 3988431 (1976-10-01), Givas et al.
patent: 3989812 (1976-11-01), Barrett et al.

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