Radiolabeled compounds for thrombus imaging

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 424 169, 424 111, 424 165, A61K 3800, C07K 500, C07K 700

Patent

active

060228571

ABSTRACT:
This invention relates to radiolabeled scintigraphic imaging agents, and methods and reagents for producing such agents. Specifically, the invention relates to specific binding compounds, including peptides, that bind to a platelet receptor that is the platelet GPIIb/IIIa receptor, methods and kits for making such compounds, and methods for using such compounds labeled with technetium-99m via a covalently-linked radiolabel-binding moiety to image thrombi in a mammalian body.

REFERENCES:
patent: 5443815 (1995-08-01), Dean et al.
patent: 5508020 (1996-04-01), Dean et al.
patent: 5552525 (1996-09-01), Dean
patent: 5645815 (1997-07-01), Dean et al.
patent: 5736122 (1998-04-01), Dean et al.

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