Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...
Patent
1997-11-18
2000-07-18
Dees, Jose' G.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Attached to antibody or antibody fragment or immunoglobulin;...
424 153, 4241441, 4241431, 4241541, 5303913, A61K 5110, A61K 4505, C07K 1600
Patent
active
060903651
ABSTRACT:
Methods for the treatment of lymphoma by administration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
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Butchko Gregory M.
Glenn Stephan D.
Kaminski Mark S.
Wahl Richard L.
Coulter Pharmaceutical, Inc.
Dees Jos,e G.
Hartley Michael G.
Regents of the University of Michigan
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