Radioimmunoassay for cyclic nucleotides

Details Radioimmunoassay for cyclic nucleotides Radioimmunoassay for cyclic nucleotides

1981-06-01

1984-02-21

Nucker, Christine M.

Chemistry: analytical and immunological testing

Involving immune complex formed in liquid phase

Separation of immune complex from unbound antigen or antibody

436539, 436804, 436815, 436828, 435 7, GO1N 3356, GO1N 3358, GO1N 3360

Patent

active

044330618

ABSTRACT:
An improved radioimmunoassay for the determination of cyclic nucleotides in body fluids which comprises adding a source of divalent cation prior to assay minimizes the effects of both endogenous calcium ion and EDTA used as an anticoagulant in blood plasma samples.

REFERENCES:
patent: 3937698 (1976-02-01), Gutcho et al.
patent: 4038033 (1977-07-01), Monks et al.
patent: 4115538 (1978-09-01), Satoh et al.
Goldberg, Clin. Chem., 23:576-580 (1977).
Tsang et al., J. Clin. Endocrinol. Met., 35:809-817 (1972).

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